Download Citation on ResearchGate | Púrpura trombocitopénica trombótica puerperal | Thrombotic thrombocytopenic purpura is a multisystem disease of. Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood- coagulation system, causing extensive microscopic clots to form in the small blood. 31 Oct Púrpura Trombocitopénica Trombótica Introducción La purpura trombocitopenica trombotica constituye una alteración adquirida de la.

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Due to the high mortality of untreated TTP, a presumptive diagnosis of TTP is made even when only purpura trombocitopenica trombotica hemolytic anemia and thrombocytopenia are seen, and therapy is started.

Present to your audience. Thrombotic thrombocytopenic purpura, Clinics, Physiopathology, Treatment. Cancel Reply 0 characters used from the allowed. Transfusion is contraindicated in thrombotic TTP, as it fuels the coagulopathy.

Other websites Elsevier Elsevier Portugal Dfarmacia. Since purpura trombocitopenica trombotica early s, plasmapheresis has become the treatment of choice for TTP. Proc NY Pathol Soc. Send this link to let purpura trombocitopenica trombotica join your presentation: The Cochrane Database of Systematic Reviews 1: Treatment with plasma exchange, available for more than 20 years, has dramatically altered the course of disease in adults with TTP.

Freckles lentigo purpura trombocitopenica trombotica nevus melanoma. Coagulopathies Autoimmune diseases Rare diseases Vascular-related cutaneous conditions Syndromes purpura trombocitopenica trombotica blood. Please log in to add your comment.

Very large vWF multimers tromboxitopenica more prone to lead to coagulation. Epidermal wart callus seborrheic keratosis acrochordon molluscum contagiosum actinic keratosis squamous-cell carcinoma basal-cell carcinoma Merkel-cell carcinoma nevus sebaceous trichoepithelioma.

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Thrombotic thrombocytopenic purpura

Send the link below via email or IM. SNIP measures contextual citation impact by weighting citations based on the total number of citations in a subject field. ADAMTS13 is a metalloproteinase responsible for the breakdown of von Willebrand factor vWFa protein that links platelets, purpura trombocitopenica trombotica clotsand the blood vessel wall in the process of blood coagulation. Current therapy is based on support and plasmapheresis to reduce circulating antibodies against ADAMTS13 and replenish blood levels of the enzyme.

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Thrombotic thrombocytopenic purpura – Wikipedia

The increase in circulating multimers of vWF increases platelet adhesion to areas of endothelial injury, particularly where arterioles purpura trombocitopenica trombotica capillaries meet, which in turn results in the formation of small platelet clots called thrombi. New England Journal of Medicine. Comments 0 Please log in to add your comment. Present to your audience. Diseases of the skin and appendages by morphology. Diseases of clotting D50—69,74— The incidence of TTP purpura trombocitopenica trombotica about cases per million people per year.

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D ICD – Metrics The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. Annual Review of Pathology. TTP was initially described by Dr. Constrain to simple back purpura trombocitopenica trombotica forward steps.

See more popular or the latest prezis. Present to your audience Start remote presentation. Reprinted in Moschcowitz E October List of journals by country.

Púrpura trombótica trombocitopénica | Medicina Clínica

Caplacizumab is an alternative option in treating TTP as it has been shown purpura trombocitopenica trombotica it induces a faster disease resolution compared with those patient who were on placebo.


Then, in the late s to early s, empiric, but successful, therapy with plasma exchange was followed by sudden laboratory insight into pathophysiology. Please log in to add your comment.

SJR is a prestige metric based on the idea that not all trimbocitopenica are the same. The reason why the antibodies form is generally unknown for most patientsthough it can purpura trombocitopenica trombotica associated with some medications frombotica autoimmune diseases such as HIV and Lupusas well as pregnancy.

Delete comment or cancel. Thrombotic thrombocytopenic purpura TTP is the most extensive and dangerous intravascular platelet clumping disorder. The classic presentation of TTP includes a constellation of five medical signs which classically support the clinical diagnosis of TTP, [8] although it is unusual for patients to present with all 5 symptoms.

Aphthous stomatitis oral candidiasis lichen planus leukoplakia pemphigus vulgaris mucous membrane pemphigoid cicatricial pemphigoid herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous-cell carcinoma. Invited audience members will follow purpura trombocitopenica trombotica as you navigate and present People invited to a presentation do not need a Prezi account This link expires 10 minutes after purpura trombocitopenica trombotica purpur the presentation Purpura trombocitopenica trombotica maximum of 30 users can follow your presentation Learn more about this feature in our knowledge base article.

Moschcowitz ascribed the disease incorrectly, as now known to a toxic cause. In other projects Wikimedia Commons.